| Authors | Zhou, KC, Dhalla, A-H, McNabb, RP, Qian, R, Farsiu, S, Izatt, JA |
| Abstract | <jats:p>Illuminating or imaging samples
from a broad angular range is essential in a wide variety of
computational 3D imaging and
resolution-enhancement techniques, such as optical projection
tomography, optical diffraction tomography, synthetic aperture
microscopy, Fourier ptychographic microscopy, structured illumination
microscopy, photogrammetry, and optical coherence refraction
tomography. The wider the angular coverage, the better the resolution
enhancement or 3D-resolving capabilities. However, achieving such
angular ranges is a practical challenge, especially when approaching <jats:inline-formula>
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</jats:inline-formula> or beyond. Often, researchers resort
to expensive, proprietary high numerical aperture (NA) objectives or
to rotating the sample or source-detector pair, which sacrifices
temporal resolution or perturbs the sample. Here, we propose several
new strategies for multiangle imaging approaching 4pi steradians using
concave parabolic or ellipsoidal mirrors and fast, low rotational
inertia scanners, such as galvanometers. We derive theoretically and
empirically relations between a variety of system parameters
(e.g., NA, wavelength, focal length, telecentricity) and achievable
fields of view (FOVs) and importantly show that intrinsic tilt
aberrations do <jats:italic toggle="yes">not</jats:italic> restrict FOV for many
multiview imaging applications, contrary to conventional wisdom.
Finally, we present strategies for avoiding spherical aberrations at
obliquely illuminated flat boundaries. Our simple designs allow for
high-speed multiangle imaging for microscopic, mesoscopic, and
macroscopic applications.</jats:p>
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